Around the world over thousands of years, patients have received root-cause holistic treatment for their diseases with personalized
treatment, diet and lifestyle modification recommendations. Read the inspiring true stories of practitioners who heal people and who recovered
from their problems after gestational-diabetes treatment at their clinics. Many have been generous to share their knowledge and experience for the benefit
of other holistic experts and patients alike. Many practitioners share their Case Studies and the healing powers of gestational-diabetes and related therapies
as they heal people who benefited from our expertise.
Relationship between Urinary Bisphenol A Levels and Diabetes Mellitus.
September 2011
Bisphenol A (BPA) is a widely used chemical in the manufacture of polycarbonate plastics and epoxy resins. Recent animal studies have suggested that BPA exposure may have a role in the development of weight gain, insulin resistance, pancreatic endocrine dysfunction, thyroid hormone disruption, and several other mechanisms involved in the development of diabetes. However, few human studies have examined the association between markers of BPA exposure and diabetes mellitus.
METHODS:
We examined the association between urinary BPA levels and diabetes mellitus in the National Health and diet therapyal Examination Survey (NHANES) 2003-2008. Urinary BPA levels were examined in quartiles. The main outcome of interest was diabetes mellitus defined according the latest American Diabetes Association guidelines.
Results:
Overall, we observed a positive association between increasing levels of urinary BPA and diabetes mellitus, independent of confounding factors such as age, gender, race/ethnicity, body mass index, and serum cholesterol levels. Compared to quartile 1 (referent), the multivariate-adjusted odds ratio (95% confidence interval) of diabetes associated with quartile 4 was 1.50 (1.05-2.14) (p-trend = 0.03). The association was present among normal-weight as well as overweight and obese subjects.Conclusions:Urinary BPA levels are found to be associated with diabetes mellitus independent of traditional diabetes risk factors. Future prospective studies are needed to confirm or disprove this finding.
/ onclick=”MoreLine(‘9348’, ‘Relationship between Urinary Bisphenol A Levels and Diabetes Mellitus.’)”>
…more
/>J Clin Endocrinol Metab. 2011 Sep 28. Epub 2011 Sep 28. PMID: 21956417
Ascorbic acid and colon cancer: an oxidative stimulus to cell death depending on cell profile.
April 2016
/ onclick=”MoreLine(‘9003’, ‘Ascorbic acid and colon cancer: an oxidative stimulus to cell death depending on cell profile.’)”>
…more
/>Eur J Cell Biol. 2016 Apr 6. Epub 2016 Apr 6. PMID: 27083410
A Randomized Controlled Clinical Trial Investigating the Effects of Omega-3 Fatty Acids and Vitamin E Co-Supplementation on Biomarkers of Oxidative Stress, Inflammation and Pregnancy Outcomes in Gestational Diabetes.
November 2016
Limited data are available for assessing the effects of omega-3 fatty acids and vitamin E co-supplementation on metabolic profiles and pregnancy outcomes in gestational diabetes (GDM). This study was designed to determine the effects of omega-3 fatty acids and vitamin E co-supplementation on biomarkers of oxidative stress, inflammation and pregnancy outcomes in women with GDM.
METHODS:
This randomized, double-blind, placebo-controlled clinical trial was conducted in 60 patients with GDM who were not taking oral hypoglycemic agents. Patients were randomly allocated to intake either 1000?mg omega-3 fatty acids from flaxseed oil plus 400?IU vitamin E supplements (n=30) or placebo (n=30) for 6 weeks. Fasting blood samples were obtained from the women at the beginning of the study and after the 6-week intervention to quantify related markers.
Results:
After 6 weeks of intervention, omega-3 fatty acids and vitamin E co-supplementation, compared with the placebo, resulted in a significant rise in total antioxidant capacity (TAC) (+187.5±224.9 vs. -32.5±136.1?mmol/L; p
/ onclick=”MoreLine(‘9002’, ‘A Randomized Controlled Clinical Trial Investigating the Effects of Omega-3 Fatty Acids and Vitamin E Co-Supplementation on Biomarkers of Oxidative Stress, Inflammation and Pregnancy Outcomes in Gestational Diabetes.’)”>
…more
/>Can J Diabetes. 2016 Nov 21. Epub 2016 Nov 21. PMID: 27881297
Vitamin E succinate induces apoptosis via the PI3K/AKT signaling pathways in EC109 esophageal cancer cells.
June 2016
/ onclick=”MoreLine(‘8988’, ‘Vitamin E succinate induces apoptosis via the PI3K/AKT signaling pathways in EC109 esophageal cancer cells.’)”>
…more
/>Mol Med Rep. 2016 Jun 27. Epub 2016 Jun 27. PMID: 27357907
Vitamin C and the risk of gestational diabetes mellitus: a case-control study.
April 1998
To examine whether low maternal dietary intake of vitamin C and low maternal plasma ascorbic acid (AA) concentrations are associated with an increased risk of gestational diabetes mellitus (GDM).
METHODS:
Cases were 67 women with GDM meeting National Diabetes Data Group criteria. Controls were 260 women without such a diagnosis. Maternal dietary vitamin C consumption during the periconceptional period and during pregnancy was assessed using a 121-item, semiquantitative food frequency questionnaire. Maternal plasma AA concentrations were determined using automated enzymatic procedures on specimens collected during the intrapartum period.
Results:
Mean maternal daily consumption of vitamin C and plasma AA concentrations were 10% and 31% lower, respectively, among GDM cases as compared with controls (130.7 +/- 10.2 vs. 145 +/- 4.9 mg/d, P = .190; 36 +/- 2.0 vs. 53 +/- 1.0 micromol/L, P12-fold increased risk of GDM (OR = 12.8, 95% CI 3.5-46.2).
Conclusion:
Low maternal dietary vitamin C intake and low plasma AA concentrations are associated with an increased risk of GDM. Large, prospective, cohort studies are needed to further evaluate the potential beneficial role of vitamin C and other antioxidants in the prevention of impaired glucose tolerance in pregnancy.
/ onclick=”MoreLine(‘8867’, ‘Vitamin C and the risk of gestational diabetes mellitus: a case-control study.’)”>
…more
/>Ann Surg. 1998 Apr;227(4):485-91. PMID: 15134150
Iron supplementation and gestational diabetes in midpregnancy.
August 2009
Iron supplementation in pregnancy seems beneficial for neonatal/maternal outcomes, but it was associated with diabetes and hypertension in the general population.
STUDY DESIGN:
We investigated the association between iron supplementation during midpregnancy and metabolic/hypertensive abnormalities in 500 consecutive gestational diabetes mellitus (GDM) and 500 normoglycemic women.
Results:
Iron-supplement users (n = 212/1000) showed significantly higher values of prepregnancy body mass index (BMI), actual BMI, waist circumference, blood pressure, fasting glucose, Homeostasis-Model-Assessment-Insulin-Resistance, and lower high-density lipoprotein-cholesterol than nonusers. The prevalence of GDM (70.8% vs 44.4%), hypertension (25.9% vs 9.8%), metabolic syndrome (25.9% vs 10.4%) was significantly higher in the former with a 2- to 3-fold-increased risk at multiple regression analyses. Most glucose values of the oral glucose tolerance test were significantly higher in iron supplemented women, both in GDM and normoglycemic individuals.
Conclusion:
Iron supplementation is associated with glucose impairment and hypertension in mid-pregnancy; its potentially harmful effects might be carefully debated regarding its effectiveness.
/ onclick=”MoreLine(‘8859’, ‘Iron supplementation and gestational diabetes in midpregnancy.’)”>
…more
/>Am J Obstet Gynecol. 2009 Aug ;201(2):158.e1-6. Epub 2009 Jun 13. PMID: 19527900