Around the world over thousands of years, patients have received root-cause holistic treatment for their diseases with personalized
treatment, diet and lifestyle modification recommendations. Read the inspiring true stories of practitioners who heal people and who recovered
from their problems after stress treatment at their clinics. Many have been generous to share their knowledge and experience for the benefit
of other holistic experts and patients alike. Many practitioners share their Case Studies and the healing powers of stress and related therapies
as they heal people who benefited from our expertise.
Resveratrol interacts with estrogen receptor-? to inhibit cell replicative growth and enhance stress resistance by upregulating mitochondrial superoxide dismutase.
January 2008
/ onclick=”MoreLine(‘10856’, ‘Resveratrol interacts with estrogen receptor-? to inhibit cell replicative growth and enhance stress resistance by upregulating mitochondrial superoxide dismutase.’)”>
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/>Chem Biol Interact. 2008 Jan 10;171(1):1-14. Epub 2007 Sep 12. PMID: 21215799
Association between fatty acid supplementation and prenatal stress in African Americans: a randomized controlled trial.
November 2014
To test the association between docosahexaenoic acid (DHA) supplementation and perceived stress and cortisol response to a stressor during pregnancy in a sample of African American women living in low-income environments.
METHODS:
Sixty-four African American women were enrolled at 16-21 weeks of gestation. Power calculations were computed using published standard deviations for the Perceived Stress Scale and the Trier Social Stress Test. Participants were randomized to either 450 mg per day of DHA (n=43) or placebo (n=21). At baseline and at 24 and 30 weeks of gestation, perceived stress was assessed by self-report. Cortisol response to a controlled stressor, the Trier Social Stress Test was measured from saliva samples collected upon arrival to the laboratory and after the completion of the Trier Social Stress Test.
Results:
Women in the DHA supplementation group reported lower levels of perceived stress at 30 weeks of gestation, controlling for depression and negative life events (mean 27.4 compared with 29.5, F [3, 47] 5.06, P=.029, Cohen’s d=0.65). Women in the DHA supplementation had lower cortisol output in response to arriving to the laboratory and a more modulated response to the stressor (F [1.78, 83.85] 6.24, P=.004, Cohen’s d=0.76).
Conclusion:
Pregnant women living in urban low-income environments who received DHA reported reduced perceived stress and lower levels of stress hormones in the third trimester. Docosahexaenoic acid supplementation may be a method for attenuating the effects of maternal stress during late pregnancy and improving the uterine environment with regard to fetal exposure to glucocorticoids. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials.gov, NCT01158976.
/ onclick=”MoreLine(‘10833’, ‘Association between fatty acid supplementation and prenatal stress in African Americans: a randomized controlled trial.’)”>
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/>Obstet Gynecol. 2014 Dec ;124(6):1080-7. PMID: 25415158
Modified apolipoprotein (apo) A-I by artificial sweetener causes severe premature cellular senescence and atherosclerosis with impairment of functional and structural properties of apoA-I in lipid-free and lipid-bound state.
May 2011
/ onclick=”MoreLine(‘9152’, ‘Modified apolipoprotein (apo) A-I by artificial sweetener causes severe premature cellular senescence and atherosclerosis with impairment of functional and structural properties of apoA-I in lipid-free and lipid-bound state.’)”>
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/>Mol Cells. 2011 May ;31(5):461-70. Epub 2011 Apr 21. PMID: 21533907
Vitamin D modifies the associations between circulating betatrophin and cardiometabolic risk factors among youths at risk for metabolic syndrome.
October 2016
Betatrophin has been recently reported to play a role in glucose homeostasis by inducing beta-cell proliferation in mice. However, studies in human are inconsistent. As a diet therapyally-regulated liver-enriched factor, we hypothesize that betatrophin might be regulated by vitamin D, and ignorance of vitamin D status may explain the discrepancy in previous human studies. The aims of this study were to assess the association between circulating betatrophin and glucose homeostasis as well as other cardiometabolic variables in a cohort of youths at risk for metabolic syndrome and test the possible influence of vitamin D status on the association.
METHODS:
559 subjects aged 14-28 years were recruited from Beijing children and adolescents metabolic syndrome study. All underwent a 2 h-oral glucose tolerance test. Serum levels of betatrophin, 25-hydroxy-vitamin D as well as adipokines including adiponectin and fibroblast growth factor 21 (FGF21) were measured by immunoassays. The relationships between betatrophin and insulin resistance, beta-cell function, other cardiometabolic variables and vitamin D status were evaluated.
Results:
Participants in the highest quartile of betatrophin levels had the highest levels of total cholesterol (P < 0.001), triglyceride (P < 0.001) and low-density lipoprotein cholesterol (P < 0.001) and the lowest levels of vitamin D (P = 0.003). After stratification by vitamin D status, betatrophin in subjects with vitamin D deficiency were positively correlated with unfavorable metabolic profiles including high blood pressures, dyslipidemia and hyperglycemia, whereas betatrophin inthose with higher vitamin D levels only showed negative association with fasting insulin, 2 h-insulin, and insulin resistance. In addition, adiponectin and FGF21 demonstrated the expected associations with metabolic parameters. CONCLUSIONS: Elevated betatrophin levels were associated with cardiometabolic risk factors in this young population, but the association was largely dependent on vitamin D status. These findings may provide valuable insights in the regulation of betatrophin and help explain the observed discrepancies in literature.
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/>Cardiovasc Diabetol. 2016 Oct 6 ;15(1):142. Epub 2016 Aug 6. PMID: 27716289
Effects of yogurt containing Lactobacillus plantarum HOKKAIDO on immune function and stress markers.
June 2016
/ onclick=”MoreLine(‘8184’, ‘Effects of yogurt containing Lactobacillus plantarum HOKKAIDO on immune function and stress markers.’)”>
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/>J Tradit Complement Med. 2016 Jul ;6(3):275-80. Epub 2015 Aug 21. PMID: 27419093
Caffeic acid phenethyl ester enhances TRAIL-mediated apoptosis via CHOP-induced death receptor 5 upregulation in hepatocarcinoma Hep3B cells.
June 2016
/ onclick=”MoreLine(‘8137’, ‘Caffeic acid phenethyl ester enhances TRAIL-mediated apoptosis via CHOP-induced death receptor 5 upregulation in hepatocarcinoma Hep3B cells.’)”>
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/>Mol Cell Biochem. 2016 Jul ;418(1-2):13-20. Epub 2016 Jun 3. PMID: 27260301