Around the world over thousands of years, patients have received root-cause holistic treatment for their diseases with personalized
treatment, diet and lifestyle modification recommendations. Read the inspiring true stories of practitioners who heal people and who recovered
from their problems after inflammation treatment at their clinics. Many have been generous to share their knowledge and experience for the benefit
of other holistic experts and patients alike. Many practitioners share their Case Studies and the healing powers of inflammation and related therapies
as they heal people who benefited from our expertise.
Zyflamend, a polyherbal preparation, inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of NF-kappa B activation and NF-kappa B-regulated gene products.
January 2007
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/>Nutr Cancer. 2007;57(1):78-87. PMID: 17516865
Antiinflammatory actions of cat’s claw: the role of NF-kappaB.
December 1998
Uncaria tomentosa is a vine commonly known as cat’s claw or ‘uña de gato’ (UG) and is used in traditional Peruvian medicine for the treatment of a wide range of health problems, particularly digestive complaints and arthritis. PURPOSE: The aim of this study was to determine the proposed anti-inflammatory properties of cat’s claw. Specifically: (i) does a bark extract of cat’s claw protect against oxidant-induced stress in vitro, and (ii) to determine if UG modifies transcriptionally regulated events.
METHODS:
Cell death was determined in two cell lines, RAW 264.7 and HT29 in response to peroxynitrite (PN, 300 microM). Gene expression of inducible nitric oxide synthase (iNOS) in HT29 cells, direct effects on nitric oxide and peroxynitrite levels, and activation of NF-kappaB in RAW 264.7 cells as influenced by UG were assessed. Chronic intestinal inflammation was induced in rats with indomethacin (7.5 mg/kg), with UG administered orally in the drinking water (5 mg/mL).
Results:
The administration of UG (100 microg/mL) attenuated (P < 0.05) peroxynitrite-induced apoptosis in HT29 (epithelial) and RAW 264.7 cells (macrophage). Cat's claw inhibited lipopolysaccharide-induced iNOS gene expression, nitrite formation, cell death and inhibited the activation of NF-kappaB. Cat's claw markedly attenuated indomethacin-enteritis as evident by reduced myeloperoxidase activity, morphometric damage and liver metallothionein expression. CONCLUSIONS: Cat's claw protects cells against oxidative stress and negated the activation of NF-kappaB. These studies provide a mechanistic evidence for the widely held belief that cat's claw is an effective anti-inflammatory agent.
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/>Aliment Pharmacol Ther. 1998 Dec;12(12):1279-89. PMID: 9882039
One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular .
July 2012
/ onclick=”MoreLine(‘11587’, ‘One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular .’)”>
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/>Am J Cardiol. 2012 Aug 1 ;110(3):356-63. Epub 2012 Apr 19. PMID: 22520621
Anti-inflammatory action of pterostilbene is mediated through the p38 mitogen-activated protein kinase pathway in colon cancer cells.
January 2006
/ onclick=”MoreLine(‘11522’, ‘Anti-inflammatory action of pterostilbene is mediated through the p38 mitogen-activated protein kinase pathway in colon cancer cells.’)”>
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/>Vestn Khir Im I I Grek. 2006;165(1):49-54. PMID: 19549798
{Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment.
November 2010
/ onclick=”MoreLine(‘11431’, ‘{Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment.’)”>
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/>Cancer Res. 2010 Nov 1;70(21):8695-705. Epub 2010 Sep 23. PMID: 20864511
Effect of atorvastatin on inflammation and outcome in patients with type 2 diabetes mellitus on hemodialysis.
December 2008
/ onclick=”MoreLine(‘11377’, ‘Effect of atorvastatin on inflammation and outcome in patients with type 2 diabetes mellitus on hemodialysis.’)”>
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/>Kidney Int. 2008 Dec;74(11):1461-7. Epub 2008 Sep 24. PMID: 18818679