Nageen Sharma
Craniosacral therapy
Federal Hostels , Faisalabad, Punjab, Pakistan, 38000
Years of experience 3

Total years in practice: 3

Published Date
December 01, 2008
Abstract Authors
Y Tan, L H K Lim
Abstract Source
Br J Pharmacol. 2008 Dec;155(7):995-1004. Epub 2008 Sep 8. PMID: 18776917
Abstract Affiliation
Inflammation and Cancer Laboratory, Department of Physiology and NUS Immunology Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Study Type
Research
Conditions
Allergies
Therapies
Functional Medicine, Naturopathic Medicine
Reference
Abstract Content
BACKGROUND AND PURPOSE: trans-Resveratrol, a non-flavonoid polyphenol found abundantly in red wine possesses antiproliferative and anti-inflammatory activity in various inflammatory conditions. However, the effect of trans-resveratrol on eosinophil activation in relation to allergy has not been investigated. EXPERIMENTAL APPROACH: Human eosinophils were isolated and purified from whole blood and incubated for 16 h with trans-resveratrol. Eosinophil chemotaxis, activation and degranulation, and apoptosis were investigated. The effect of trans-resveratrol on the inhibition of p38 and ERK1/2 activation was examined. KEY
Results:
Treatment of human eosinophils with trans-resveratrol at concentrationsCONCLUSIONS AND IMPLICATIONS: trans-Resveratrol is effective at inhibiting human eosinophil activation and degranulation at concentrations
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