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Hyperuricemia research studies for holistic treatments

Around the world over thousands of years, patients have received root-cause holistic treatment for their diseases with personalized
treatment, diet and lifestyle modification recommendations. Read the inspiring true stories of practitioners who heal people and who recovered
from their problems after hyperuricemia treatment at their clinics. Many have been generous to share their knowledge and experience for the benefit
of other holistic experts and patients alike. Many practitioners share their Case Studies and the healing powers of hyperuricemia and related therapies
as they heal people who benefited from our expertise.

/ title=”Efficacy Of Virechana Karma And Vamana Purvaka Virechana Karma In The Management Of Ekakushta W.S.R. Psoriasis – A Comparative Study”>
Efficacy Of Virechana Karma And Vamana Purvaka Virechana Karma In The Management Of Ekakushta W.S.R. Psoriasis – A Comparative Study

November 2014

Healthy skin is the reflection of healthy body where in the affliction of former will not only have an impact on somatic make-up but also on psychological and social aspects of an individual. Among various varieties of Kushta (leprosy), Ekakushta takes upper hand by the way of its chronicity, severity, involving large extent of body parts, difficulty in its curability and is often compared to Psoriasis, a chronic, non-infectious skin disease characterized by well defined, slightly raised, dry, silvery erythematous macules and typical extensor distribution. Ekakushta, as it is predominant of Vata – Kapha dosha, the first line of treatment that comes into picture is Vamana Karma (Emesis Therapy). The prime cause for the manifestation of Kushta is mostly Viruddha Ahara (unwholesome food) which has to be handled by administering Virechana Karma (Purgation Therapy) and Vamana Karma (Emesis Therapy). In toto, the line of treatment of Kushta speaks about both Vamana Karma and Virechana Karma. In this regard, an approach of treatment blended with both Vamana Karma and Virechana Karma may be more effective in treating the disease Ekakushta. Hence, a comparative study was taken up to evaluate the effect of Virechana Karma in Group A and Vamana poorvaka Virechana Karma {Kramataha Shodhana (repetitive purification)} in Group B in the management of Ekakushta w.s.r. to Psoriasis and the results were statistically analysed.

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/ title=”Blueberry Consumption Affects Serum Uric Acid Concentrations in Older Adults in a Sex-Specific Manner.”>
Blueberry Consumption Affects Serum Uric Acid Concentrations in Older Adults in a Sex-Specific Manner.

November 2016

Blueberries are rich in antioxidants and may protect against . Uric acid accounts for about 50% of the antioxidant properties in humans. Elevated levels of serum uric acid (SUA) or hyperuricemia is a risk factor for cardiovascular (CVD). The aim was to determine the effect of blueberries on SUA in older adults. Participants (n = 133, 65-80 years) experiencing mild cognitive impairment (MCI) were randomized in a double-blind 6-month clinical trial to either blueberry or placebo. A reference group with no MCI received no treatment. The mean (SD) SUA at baseline were 5.45 (0.9), 6.4 (1.3) and 5.8 (1.4) mg/dL in reference, placebo, and treatment groups, respectively. Baseline SUA was different in men and women (6.25 (1.1) vs. 5.35 (1.1), p = 0.001). During the first three months, SUA decreased in the blueberry group and was significantly different from the placebo group in both men and women (p

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/ title=”Inhibition of monosodium urate crystal-induced inflammation by withaferin A.”>
Inhibition of monosodium urate crystal-induced inflammation by withaferin A.

January 2008

PURPOSE: Gouty arthritis is a characteristically intense acute inflammatory reaction resulting from the formation of sodium urate crystals in the joint cavity. In the present study, the effect of withaferin A, a steroidal lactone was investigated on monosodium urate crystal-induced inflammation in mice; an experimental model for gouty arthritis and compared it with that of the non-steroidal anti-inflammatory drug, indomethacin.
METHODS:
Paw volume and levels/activities of lysosomal enzymes, lipid peroxidation, anti-oxidant status and inflammatory mediator TNF-alpha were determined in control and monosodium urate crystal-induced mice. The levels of beta-glucuronidase and lactate dehydrogenase were also measured in monosodium urate crystal-incubated polymorphonuclear leucocytes (PMNL).
Results:
Paw volume, the levels of lysosomal enzymes, lipid peroxidation, and inflammatory mediator tumour necrosis factor-alpha were found to be increased significantly and the activities of antioxidant status were in turn decreased in monosodium urate crystal-induced mice; however these changes were reverted back to near normal levels in withaferin A (30 mg/kg/b.wt, i.p.) treated monosodium urate crystal-induced mice. In addition, beta-glucuronidase and lactate dehydrogenase level were reduced in withaferin A (100microg/ml) treated monosodium urate crystal-incubated polymorphonuclear leucocytes.
Conclusion:
The present findings clearly indicated that withaferin A exerted a strong anti-inflammatory effect against gouty arthritis.

/ onclick=”MoreLine(‘9367’, ‘Inhibition of monosodium urate crystal-induced inflammation by withaferin A.’)”>
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/ title=”Pycnogenol attenuates the inflammatory and nitrosative stress on joint inflammation induced by urate crystals.”>
Pycnogenol attenuates the inflammatory and nitrosative stress on joint inflammation induced by urate crystals.

February 2012

Acute gouty arthritis results from monosodium urate (MSU) crystal deposition in joint tissues. Deposited MSU crystals induce an acute inflammatory response which leads to damage of joint tissue. Pycnogenol (PYC), an extract from the bark of Pinus maritime, has documented antiinflammatory and antioxidant properties. The present study aimed to investigate whether PYC had protective effects on MSU-induced inflammatory and nitrosative stress in joint tissues both in vitro and in vivo. MSU crystals upregulated cyclooxygenase 2 (COX-2), interleukin 8 (IL-8) and inducible nitric oxide synthase (iNOS) gene expression in human articular chondrocytes, but only COX-2 and IL-8 in synovial fibroblasts. PYC inhibited the up-regulation of COX-2, and IL-8 in both articular chondrocytes and synovial fibroblasts. PYC attenuated MSU crystal induced iNOS gene expression and NO production in chondrocytes. Activation of NF-?B and SAPK/JNK, ERK1/2 and p38 MAP kinases by MSU crystals in articular chondrocytes and synovial fibroblasts in vitro was attenuated by treatment with PYC. The acute inflammatory cell infiltration and increased expression of COX-2 and iNOS in synovial tissue and articular cartilage following intra-articular injection of MSU crystals in a rat model was inhibited by coadministration of PYC. Collectively, this study demonstrates that PYC may be of value in treatment of MSU crystal-induced arthritis through its anti-inflammatory and anti-nitrosative activities.

/ onclick=”MoreLine(‘9357’, ‘Pycnogenol attenuates the inflammatory and nitrosative stress on joint inflammation induced by urate crystals.’)”>
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/ title=”[Evaluation of hyperuricemia caused by fructose in a status of altered uric acid metabolism].”>
[Evaluation of hyperuricemia caused by fructose in a status of altered uric acid metabolism].

December 1987

It’s reported that oral administration of fructose in normal and gouty patients causes a rise in serum uric acid (see “References”: Stirpe et al.). The changes in serum uric acid after administration of fructose to gouty patients and to children of gouty patients were significantly different from the changes observed in normal subjects, both for the extent and for the duration of hyperuricaemia. In this study the authors verify if the fructose-induced hyperuricaemia can help to identify gouty patients from people with different metabolic alteration of serum uric acid levels (i.e. chronic leukaemias and some neoplastic s).

/ onclick=”MoreLine(‘7687’, ‘[Evaluation of hyperuricemia caused by fructose in a status of altered uric acid metabolism].’)”>
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/ title=”[Inhibition of fructose-induced hyperuricacidemia by pretreatment with phosphates].”>
[Inhibition of fructose-induced hyperuricacidemia by pretreatment with phosphates].

April 1982

To test the hypothesis that intravenous injections of fructose rapidly decreases liver ATP and Pi and results in the rapid degradation of adenine nucleotides and hyperuricemia, fructose was administered intravenously to a group of normal and gouty subjects; 4 gouty patients were treated with a phosphate solution prior fructose loading. The results obtained show that fructose administration plus phosphate solution prevents Pi depletion and inhibits fructose-induced hyperuricemia.

/ onclick=”MoreLine(‘7686’, ‘[Inhibition of fructose-induced hyperuricacidemia by pretreatment with phosphates].’)”>
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